I've been stalling on setting up things on the Mojave side, so that as many things that would need patches would get them while I explored DC. Now I'm wanting to play the game fully decked-out with mods, and I set up all of the stuff that interested me in the Recommended Mods list. I also did it because I had never been able to get FO3 to work without constant crashing without using TTW.
I had wanted to see the vanilla experience before modding the game, and I didn't have any of the DLC before playing TTW, so I did the same thing. I've only played New Vegas with nothing but some user interface mods, and when I played the older version of TTW, I played it pretty much the same way, but with the Goodsprings schoolhouse player home so that I'd have a player home upon starting the Mojave.